Cannabinoid concentrations in hair from documented cannabis users
نویسندگان
چکیده
منابع مشابه
Differentiating new cannabis use from residual urinary cannabinoid excretion in chronic, daily cannabis users.
AIMS To develop and validate empirically a mathematical model for identifying new cannabis use in chronic, daily cannabis smokers. DESIGN Models were based on urinary creatinine-normalized (CN) cannabinoid excretion in chronic cannabis smokers. SETTING For model development, participants resided on a secure research unit for 30 days. For model validation, participants were abstinent with da...
متن کاملJust say 'know': how do cannabinoid concentrations influence users' estimates of cannabis potency and the amount they roll in joints?
AIMS (1) To determine whether measured concentrations of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in individuals' own cannabis predict their estimates of drug potency and actual titration; and (2) to ascertain if these effects are influenced by frequency of use and cannabis type. DESIGN Cross-sectional, naturalistic. SETTING Participants' own homes. PARTICIPANTS A total of...
متن کاملComparison of Cannabinoid Concentrations in Plasma, Oral Fluid and Urine in Occasional Cannabis Smokers After Smoking Cannabis Cigarette.
PURPOSE A randomized cross-over, double blind placebo controlled study of smoked cannabis was carried out on occasional cannabis smokers. The objective of this research was to describe the pharmacokinetic parameters of THC and its metabolites in plasma, oral fluid and urine, from samples obtained simultaneously to provide estimations of THC and metabolites concentrations after smoking a cannabi...
متن کاملDecreased Spontaneous Eye Blink Rates in Chronic Cannabis Users: Evidence for Striatal Cannabinoid-Dopamine Interactions
Chronic cannabis use has been shown to block long-term depression of GABA-glutamate synapses in the striatum, which is likely to reduce the extent to which endogenous cannabinoids modulate GABA- and glutamate-related neuronal activity. The current study aimed at investigating the effect of this process on striatal dopamine levels by studying the spontaneous eye blink rate (EBR), a clinical mark...
متن کاملComparison of cannabinoids in hair with self‐reported cannabis consumption in heavy, light and non‐cannabis users
INTRODUCTION Biological tests of drug use can be used to inform clinical and legal decisions and hold potential to provide evidence for epidemiological studies where self-reported behaviour may be unavailable or unreliable. We test whether hair can be considered as a reliable marker of cannabis exposure. METHODS Hair samples were collected from 136 subjects who were self-reported heavy, light...
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ژورنال
عنوان ژورنال: Forensic Science International
سال: 2007
ISSN: 0379-0738
DOI: 10.1016/j.forsciint.2006.08.005